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Product Info Summary
| SKU: | A05158-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IF, WB |
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Product info
Product Name
Anti-TNF Alpha-IP8 TNFAIP8 Antibody
SKU/Catalog Number
A05158-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-TNF Alpha-IP8 TNFAIP8 Antibody catalog # A05158-1. Tested in WB,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TNF Alpha-IP8 TNFAIP8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05158-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human TFIP8.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05158-1 is reactive to TNFAIP8 in Human, Mouse, Rat
Applications
A05158-1 is guaranteed for IF, WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
23.003kDa
Background of TNFAIP8
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Horrevoets A.J.G., Blood 93:3418-3431(1999).
Kumar D., J. Biol. Chem. 275:2973-2978(2000).
You Z., J. Biol. Chem. 276:26398-26404(2001).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IF: 1:50-1:200
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-TNF Alpha-IP8 TNFAIP8 Antibody A05158-1
Western blot (WB) analysis of TNFα-IP8 polyclonal antibody at 1:500 dilutionLane1:HEK293T cell lysate
Lane2:Raw264.7 cell lysate
Lane3:H9C2 cell lysate
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For TNFAIP8 (Source: Uniprot.org, NCBI)
Gene Name
TNFAIP8
Full Name
Tumor necrosis factor alpha-induced protein 8
Weight
23.003kDa
Superfamily
TNFAIP8 family
Alternative Names
GG2-1; Head and neck tumor and metastasis-related protein; MDC-3.13TNF-induced protein GG2-1; NDED; NF-kappa-B-inducible DED-containing protein; SCC-S2SCCS2; TNF alpha-induced protein 8; tumor necrosis factor alpha-induced protein 8; tumor necrosis factor, alpha-induced protein 8 TNFAIP8 GG2-1, MDC-3.13, NDED, SCC-S2, SCCS2 TNF alpha induced protein 8 tumor necrosis factor alpha-induced protein 8|NF-kappa-B-inducible DED-containing protein|TNF-induced protein GG2-1|head and neck tumor and metastasis-related protein|tumor necrosis factor, alpha induced protein 8
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TNFAIP8, check out the TNFAIP8 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TNFAIP8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TNF Alpha-IP8 TNFAIP8 Antibody (A05158-1)
Hello CJ!
No publications found for A05158-1
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